Question 1

What is NAD+?

Accepted Answer

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential to energy metabolism, DNA repair and sirtuin enzyme activity. Declining NAD+ levels with age are one of the most studied phenomena in longevity research, which is why the compound and its precursors dominate the field.

Question 2

What is the difference between NAD+, NMN and NR?

Accepted Answer

NMN and NR are oral precursor molecules that cells convert into NAD+. Research-grade NAD+ itself is typically studied via injection in laboratory settings, since the molecule is poorly absorbed orally. Which form a study uses depends on the research question — precursor conversion versus direct NAD+ availability. Our NAD vs NMN vs NR article covers the published comparisons.

Question 3

Why is NAD+ studied in longevity research?

Accepted Answer

NAD+ is the required substrate for sirtuins (enzymes linked to cellular ageing regulation) and PARPs (DNA-repair enzymes). Published research shows cellular NAD+ levels decline substantially with age, and restoring them is a central hypothesis in ageing research — studied across metabolism, DNA repair and mitochondrial-function models.

Question 4

Is NAD+ legal to buy in the UK?

Accepted Answer

Yes — NAD+ is not a controlled substance and can be lawfully supplied for laboratory research purposes. Research-grade injectable NAD+ is not a licensed medicine and is not sold for human consumption.

Question 5

Is RegenMed NAD+ third-party tested?

Accepted Answer

Yes. Every batch is independently tested by an external laboratory for identity and purity, with certificates of analysis available on request.

Compound	What it is	Typical research use
NAD+	The coenzyme itself	Direct-availability studies, typically injectable in laboratory settings due to poor oral absorption
NMN	Immediate precursor (one enzymatic step from NAD+)	Oral supplementation studies of precursor conversion
NR	Earlier precursor (converted via NMN)	Oral supplementation studies; the most human-trialled precursor

NAD+ in the UK: the longevity research coenzyme

NAD+ vs NMN vs NR: which form appears in research

Longevity research compounds

What is NAD+?

What is the difference between NAD+, NMN and NR?

Why is NAD+ studied in longevity research?

Is NAD+ legal to buy in the UK?

Is RegenMed NAD+ third-party tested?

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